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Potential Treatment for Neuropathy Caused by Eloxatin

by Donna Myers
for About.com

Updated: May 5, 2007

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Eloxatin (oxaliplatin) is a chemotherapy drug that is often used to treat colorectal cancer. But, patients who receive Eloxatin often experience neuropathy, which literally means a problem with the nerves.

Symptoms of neuropathy may include numbness and tingling in your fingers, toes, or throat; sensitivity to cold; a reduced sense of touch; and a "pins and needles" kind of feeling in your hands and feet. When neuropathy occurs, cancer patients must make a difficult decision: deal with it or cut back on (or stop) the Eloxatin.

A study published in The Oncologist may offer another option: oral glutamine. According to the researchers, supplementing a colorectal cancer patient's chemo with oral glutamine reduced the incidence and severity of neuropathy without adversely affecting the efficacy of the chemo.

Related Research Summaries:

Sources:

  1. Wang, W. and Lin, J. "Oral Glutamine Is Effective for Preventing Oxaliplatin-Induced Neuropathy in Colorectal Cancer Patients." The Oncologist 12.3 (Mar. 2007): 312-319. Accessed 7 April 2007.
  2. "Your Treatment with Eloxatin: A Patient's Guide." Sanofi-Aventis. Nov. 2006. Accessed 7 April 2007 [http://www.eloxatin.com/docs/pdf/Pt%20Brochure%20Final.pdf].

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